Uses of antileukoprotease in carcinoma
AssigneeBoard of Trustees of the University of Arkansas
InventorsTimothy J. O' Brien, Lowell J. Underwood, Hirotoshi Tanimoto, Kazushi Shigemasa
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Abstract
The present invention provides a method of detecting/monitoring tumor growth and progression in a tissue by measuring the level of antileukoprotease. Also provided is a method of treating an individual having a tumor by administering antileukoprotease to inhibit the activity of stratum corneum chymotryptic enzyme. Specifically, the tumor is an ovarian carcinoma.
Claims15
A method of detecting growth of an ovarian tumor and ovarian-derived metastatic tumor in a sample from an individual, comprising the step of:
- measuring the level of antileukoprotease in said individual, wherein if said level of antileukoprotease exceeds the mean basal level of antileukoprotease in nondiseased individuals by 2 standard deviation or greater, said individual has growth in an ovarian or ovarian-derived tumor.
A method of treating an individual having a tumor selected from the group consisting of an ovarian tumor and ovarian-derived metastatic tumors, comprising the step of:
- administering antileukoprotease to said individual.
A method of preventing metastasis of a tumor selected from the group consisting of an ovarian tumor and ovarian derived metastatic tumors, comprising the step of:
- administering antileukoprotease to an individual having said tumor.
Dependencies are inferred from the claim text.