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AssigneeThe Johns Hopkins University
InventorsClaire M. Fraser, Mark D. Adams, Jeannine D. Gocayne, Clyde A. Hutchison III, Hamilton O. Smith, J. Craig Venter, Owen R. White
Estimating the term…
The present invention provides the nucleotide sequence of the entire genome of Mycoplasma genitalium, SEQ ID NO: 1. The present invention further provides the sequence information stored on computer readable media, and computer-based systems and methods which facilitate its use. In addition to the entire genomic sequence, the present invention identifies protein encoding fragments of the genome, and identifies, by position relative to two (2) genes known to flank the origin of replication, any regulatory elements which modulate the expression of the protein encoding fragments of the Mycoplasma genitalium genome.
An isolated polynucleotide comprising the nucleotide sequence of any one of the fragments of SEQ ID NO:
An isolated polynucleotide comprising a nucleic acid sequence which hybridizes under hybridization conditions comprising hybridization in 5×SSC and 50% formamide at 50° C. and washing in a wash buffer consisting of 0.5× SSC at 65° C., to the complementary strand of any one of the fragments of SEQ ID NO:
An isolated polynucleotide comprising at least 50 contiguous nucleotides of any one of the fragments of SEQ ID NO:
Dependencies are inferred from the claim text.