Bioavailability enchancing activity of Zingiber officinale Linn and its extracts/fractions thereof

A process for the preparation of an aqueous extract, aq.alcoholic extract and bioactive fraction from the plant Zingiber officinale, said process comprises steps of:

• a) extracting crushed plant material with water or aqueous alcoholic solvent at a temperature range of 95-100° C.;
• b) cooling and filtering the extract of step (a) to obtain a clear aqeuous extract or aqueous alcoholic extract;
• c) evaporating the aq.extract of step (b) under reduced pressure at 60° C. to obtain an concentrated aqueous extract;
• d) freeze drying the concentrated aqueous extract of step (c) to obtain a dried aqueous extract;
• e) evaporating the solvent from aqueous alcoholic extract of step (b);
• f) macerating dried aqueous alocholic extract obtained from step (e) of with chloroform,
• g) separating the chloroform soluble fraction from step (f) to obtain fraction 1 and an insoluble fraction;
• h) dissolving the insoluble fraction from step (g) in water and adding alcoholic solvent, stirring and filtering the mixture to separate aqueous alcohol soluble portion and a residue;
• i) distilling the aqueous alcohol soluble fraction of step (h) under reduced pressure to obtain fraction 2;
• and
• j) dissolving the residue of step (i) in water and freeze drying it to get fraction 3.