Streptomyces megasporus sd5, process for the isolation thereof, novel fibrinolytic enzyme prepared therefrom, process for the production of said enzyme and method of treatment of thrombolytic disorders using said enzyme
AssigneeMaharashtra Assoc. for the Cultivation of Science
InventorsRatnakar Ravindra Chitte, Sabita Dey
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Abstract
The present invention relates to a novel microorganism Streptomyces megasporus SD5. The present invention also relates to a process for the isolation of said Streptomyces megasporus SD5. The invention also relates to a novel fibrinolytic enzyme actinokinase extracted from said microorganism and to a process for the extraction of said enzyme. In another aspect, the invention also pertains to a method for the treatment of thrombolytic disorders using said enzyme.
Claims32
A novel strain of Streptomyces named Streptomyces megasporus SD5 and variants and mutants thereof.
A process for the isolation of the microorganism Streptomyces megasporus SD5 from hot water sources and springs using a nutrient medium containing carbon and nitrogen sources in a definite ratio and inorganic nutrient salts.
A novel enzyme extracted from the microorganism Streptomyces megasporus SD5 useful as a thrombolytic agent.
A process for the preparation of a novel enzyme from the microorganism Streptomyces megasporus SD5 D comprising cultivating the microorganism Streptomyces megasporus SD5 or a variant or mutant thereof under aerobic conditions at a temperature in the range of 45° C. to 65° C. in an alkaline aqueous nutrient medium and recovering the enzyme.
Dependencies are inferred from the claim text.