Method for producing a bio-artificial transplant
OwnerAugustinus Baderinventor
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Abstract
The invention relates to a method for producing a bioartificial transplant from biological tissue provided for transplantation, which has cells that are compatible with the recipient applied thereto. According to the invention, a controlled tissue generation is carried out in-vitro, during which selected cells that are capable of remodelling the carrier structures are added to native tissue that is maintained in a culture and the culture is continued until a new tissue which has been substantially transformed is obtained, said tissue containing the added recipient-compatible cells.
Claims18
A process for the production of a bioartificial transplant from a biological tissue intended for transplantation and recipient-tolerable cells applied thereto, characterized in that
- recipient-tolerable cells which comprise at least selected cells capable of remodelling of the carrier structures are added in a conditioning medium to the autologous, allogenic or xenogenic tissue intended for the transplant, present in native form and not pretreated with exogenous growth factors,
- the treatment of the transplant is continued until an extensive transformation of the original native tissue into a tissue essentially containing the added recipient-tolerable cells has been achieved.
Dependencies are inferred from the claim text.