Treatment of actinomyces naeslundii-related diseases with exogenous lactic bacteria strains
OwnerElena-Maria Comelli, Bernhard Guggenheim +2inventors
InventorsElena-Maria Comelli, Bernhard Guggenheim, Jean-Richard Neeser, Francesca Stingele
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Abstract
A lactic bacteria strain that is exogenous to the oral microflora is selected for its ability to adhere the pellicle of the teeth and to produce a growth inhibition factor. This strain is used for the preparation of a composition intended for reducing dental plaque and for treating or preventing root caries and other diseases related to Actinomyces naeslundii in mammals.
Claims19
A method for reducing dental plaque or for treating or preventing root caries or other diseases related to Actinomyces naeslundii in mammals which comprises administering to a mammal in need of such treatment a lactic bacteria strain that is exogenous to the oral microflora, which strain is selected for its ability to adhere to teeth pellicle and to produce a growth inhibition factor, in a therapeutically effective amount.
A method for making a composition that is effective for reducing dental plaque or for treating or preventing root caries or other diseases related to Actinomyces naeslundii in mammals which comprises incorporating in an edible composition a lactic bacteria strain that is exogenous to the oral microflora, which strain is selected for its ability to adhere to teeth pellicle and to produce a growth inhibition factor, and which is present in a therapeutically effective amount.
A composition for maintaining mammal mouth health by reducing Actinomyces naeslundii colonization therein, the composition comprising at least one lactic bacteria strain that is exogenous to oral microflora, which strain is selected for its ability to adhere to teeth pellicle and to produce a growth inhibition factor, and which is present in a therapeutically effective amount.
A method for the prevention or the treatment of Actinomyces naeslundii-related diseases in mammals, which comprises administering to a mammal a therapeutically effective amount of at least one lactic bacteria strain which is selected for its ability to adhere to teeth pellicle and to produce a growth inhibition factor.
A dentifrice composition for maintaining mammal mouth health by reducing Actinomyces naeslundii colonization therein, the composition comprising at least one lactic bacteria strain that is exogenous to oral microflora, which strain is selected for its ability to adhere to teeth pellicle and to produce a growth inhibition factor, and which is present in a therapeutically effective amount.
Dependencies are inferred from the claim text.