Reaction chamber roll pump

A method for circulating and mixing solution within a microarray package and reaction chamber, the method comprising:

• providing a microarray package and reaction chamber comprising a pocket, a microarray positioned to substantially cover the pocket, an active surface of the microarray on which features have been deposited facing into the pocket, and a flexible cover sealed to the pocket to enclose the microarray in an enclosed package and reaction chamber;
• introducing solution into the reaction chamber;
• and
• rotating the reaction chamber so that solution repeatedly flows from the pocket across the active surface of the microarray and back into the pocket.

A method for circulating and mixing solution within a microarray package and reaction chamber, the method comprising:

• providing a microarray package and reaction chamber comprising a pocket, a microarray positioned to substantially cover the pocket, an active surface of the microarray on which features have been deposited facing into the pocket, a dispersion membrane mounted parallel to, and in close proximity with, the active surface of the microarray, and a flexible cover sealed to the pocket to enclose the microarray in an enclosed package and reaction chamber;
• introducing solution into the reaction chamber;
• and
• rotating the reaction chamber so that solution repeatedly flows from the pocket into a reaction-fluid/dispersion-membrane medium in contact with the active surface of the microarray and back into the pocket.