Reaction block for parallel synthetic chemistry and vessel therefor
OwnerDieter Voegelin, Roman Bar +1inventors
InventorsDieter Voegelin, Roman Bar, Claus Muller
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Abstract
A reaction vessel for use in an apparatus for parallel synthetic chemistry with a reaction chamber space for containing contents of a chemical reaction and a discharge channel for selectively removing liquid contents of the reaction chamber. The invention includes an apparatus for receiving a plurality of the reaction vessels, a method for using the apparatus and a method for forming the vessels.
Claims28
A reaction vessel for performing chemical reactions, particularly for use in parallel chemical synthesis or analysis, comprising
- a body made of a polymeric material, shapable by injection molding, said body defining a reaction chamber and a discharge channel, said reaction chamber and said discharge channel each having an open end and a bottom portion, and
- a fluidic connection channel connecting the discharge channel with the space within the reaction chamber, where a reaction medium is received and
- the reaction chamber and the discharge channel each extending from its open end towards its bottom portion with constant or decreasing cross section.
A reaction vessel for performing chemical reactions, for use in parallel chemical synthesis or analysis, comprising
- a body made of a thermoplastic polymeric material, said body defining a reaction chamber defining a longitudinal axis, having a space therein for receiving a reaction medium and a discharge channel, said reaction chamber space and said discharge channel each having an open end and a bottom portion, and
- a fluidic connection channel connecting the discharge channel with the the reaction chamber space, and
- the reaction chamber and the discharge channel each extending from its open end towards its bottom portion with constant or decreasing cross section.
A method for manufacturing a reaction vessel having a body defining a reaction chamber space therewithin comprising
- forming said body of said vessel by injection molding of a polymeric material in an injection mold,
- shaping an interior of a discharge channel by a first core and an interior of the reaction chamber by a second core,
- moving said first and second core into the mold before an injection of a molten polymeric material into the mold and retracting said first core and said second core after allowing a sufficient time for the molten polymeric material to solidify during opening of the mold
- said second core for shaping the reaction chamber bearing a movable extension at an end thereof for forming the bottom of the reaction chamber, and said extension touching the first core when said first and second core disposed in the mold thereby forming said connection channel between said reaction chamber and said discharge channel.
Dependencies are inferred from the claim text.