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US 2003/0167093 A1Published application
Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates
AssigneeAmerican Dental Association Health Foundation
InventorsHuakun Xu, Laurence C. Chow, Shozo Takagi, Frederick C. Eichmiller
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Abstract
A bone replacement material and therapy comprises the combination of calcium phosphate compounds and two or more soluble fillers in the form of fibers, mesh or other materials which have the dual functions of reinforcing an in vivo implant while dissolving at a programmed rate to form macropores capable of receiving natural bone ingrowth.
Claims32
A bone material and hard tissue replacement material comprising, in combination, a mixture of:
- a calcium phosphate compound capable of forming a chemically compatible in vivo bone or hard tissue replacement composition;
- and
- at least first and second macropore forming materials, said first and second macropore forming materials each have a distinct dissolution rate in vivo.
A method of bone replacement comprising the steps of:
- (a) mixing the composition of any of claim 1-24;
- and
- (b) placing said mixture in vivo.
Dependencies are inferred from the claim text.