Method of radiotherapy
AssigneeAlgeta A/S
InventorsRoy Larsen, Gjermund Henriksen
Life of this patent
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Abstract
The invention provides a method of radiation treatment of a human or non-human mammalian subject which comprises administering to said subject a therapeutically, prophylactically or pain-palliating amount of a bone-targeting complex of an alpha-particle emitting thorium or actinium radionuclide, e.g. for the treatment of calcified tumors, bone tumors, bones, bone surfaces an soft tissues.
Claims17
In a method of radiation treatment of a human or non-human mammalian subject which comprises administering to said subject a therapeutically, prophylactically or pain-palliating amount of a bone-targeting complex of a radionuclide, the improvement comprising using as said radionuclide a radionuclide selected from the group consisting of alpha-particle emitting thorium and actinium radionuclides.
The use of an alpha particle emitting thorium or actinium radionuclide, or a bone-targeting complex thereof, for the manufacture of a medicament for use in a method of radiation treatment of a human or non-human mammalian subject which comprises administering to said subject a bone-targeting complex of said radionuclide.
A radiopharmaceutical composition comprising a bone-targeting complex of a radionuclide selected from alpha-particle emitting thorium and actinium radionuclides, together with at least one physiologically acceptable carrier or excipient.
A bone-targeting complex of a radionuclide selected from alpha-particle emitting thorium and actinium radionuclides.
A kit for the treatment of bone surfaces or primary and/or metastatic cancers to the skeleton, comprising:
- an alpha-particle emitting actinium or thorium radioisotope, and a bone seeking chelator, for the preparation of physiologically compatible solutions of, an actinium or thorium radioisotope chelate;
- a pharmaceutically acceptable carrier;
- and, optionally, administration equipment.
Dependencies are inferred from the claim text.