4-Substituted piperidine compound
AssigneeEisai Co., Ltd.
InventorsYoichi Iimura, Takashi Kosasa
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Abstract
The present invention provides a novel compound having a superior acetylcholinesterase inhibitory action. It provides a compound represented by the formula: 1 (In the formula, R1 represents a group represented by the formula: 2 (wherein, R3, R4, R5 and R6 are the same as or different from each other and each represents a hydrogen atom, an optionally substituted C1-6 alkoxy group and the like; and m represents an integer from 0 to 6) and the like; and R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted C2-6 alkenyl group or an optionally substituted C2-6 alkynyl group), a salt thereof or a hydrate of them.
Claims21
A compound represented by the formula:
- 21
- (in the formula, R1 represents any one of group selected from the group consisting of the formulae:
- 22 23
- (wherein, R3, R4, R5 and R6 are the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, an optionally substituted hydrocarbon group, an optionally substituted C1-6 alkoxy group, a C1-6 acyl group, a nitro group, an optionally substituted amino group, an optionally substituted amide group, a mercapto group or a C1-6 thioalkoxy group;
- R7 represents a hydrogen atom or a C1-6 alkyl group;
- the partial structure represents a single bond or a double bond;
- m is 0 or an integer from 1 to 6;
- and p represents an integer of 1 or 2);
- and R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, an optionally substituted C2-6 alkenyl group or an optionally substituted C2-6 alkynyl group), a salt thereof or a hydrate of them.
Dependencies are inferred from the claim text.