Mucin peptide with immunoenhancing properties
AssigneeUniversity of Miami
InventorsDiana M. Lopez, Lynn M. Herbert, Mantley Dorsey JR., Gunter Kraus, H. James Hnatyszyn
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Abstract
An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO: 1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and methods of use. The peptide or polypeptide may be conjugated to a carrier protein and administered as part of a vaccine or immunogenic composition for prevention or treatment of a disease or disorder.
Claims20
An isolated peptide or polypeptide comprising amino acid sequence VSIGLSFPMLP (SEQ ID NO:
- 1), or an analog or derivative thereof, said peptide or polypeptide having the property of enhancing an immune response to an antigen when administered to a mammal.
Dependencies are inferred from the claim text.