Immunogenic pneumococcal protein and vaccine compositions thereof
AssigneeMedImmune, LLC
InventorsScott Koenig, Leslie S. Johnson, John E. Adamou
Life of this patent
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Abstract
The present invention relates to novel immunogenic polypeptides, and therapeutically active fragments thereof, and vaccines, and vaccine compositions, for the prevention and treatment of streptococcal infection, especially by Streptococcus pneumoniae. The invention also relates to antibodies against the disclosed polypeptides, as well as methods of disease prevention and/or treatment.
Claims29
An isolated polypeptide comprising an amino acid sequence at least about 80% identical to the amino acid sequence of SEQ ID NO:
- 4.
An isolated polynucleotide comprising a nucleotide sequence at least 65% identical to a polynucleotide sequence encoding the polypeptide of SEQ ID NO 4.
Dependencies are inferred from the claim text.