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US 2003/0166837 A1Published application
Isolated molecules which complex with HLA-Cw*16 molecules, and uses thereof
OwnerPierre van der Bruggen, Etienne DePlaen +1inventors
InventorsPierre van der Bruggen, Etienne DePlaen, Thierry Boon-Falleur
Life of this patent
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Abstract
The invention involves the identification of peptides which complex with HLA-Cw*16 molecules, and which may then provoke lysis of the cells to which they bind, by cytolytic T cells. Diagnostic and therapeutic uses are described.
Claims17
Isolated peptide consisting of amino acid sequence
- Xaa Ile (Xaa)4 Arg (Xaa)2 Tyr Xaa
- wherein the first Xaa is from 0-3 amino acids in length, the fourth Xaa is 0-2 amino acids in length, and the first and fourth Xaa are no more than 3 amino acids in total, each Xaa is any amino acid, and said peptide binds to an HLA-Cw16 molecule.
Isolated nucleic acid molecule consisting of nucleotides 1033 through 1104 of cDNA for MAGE-6.
Dependencies are inferred from the claim text.