Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
AssigneeBoehringer Ingelheim Pharma GmbH & Co. KG
InventorsAnke Esperester, Uwe Pschorn, Jean-Michel Vix
Life of this patent
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Abstract
The invention relates to the use of ambroxol and the pharmacologically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of painful conditions in the oral and pharyngeal cavity.
Claims12
Use of ambroxol or one of the pharmacologically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of pain in the oral and/or pharyngeal cavity, selected from among acute sore throat, aphthae, gingivitis, parodontopathies, pressure points caused by prostheses, pain after oro-pharyngeal interventions, lesions on the mucous membrane in the oral and pharyngeal cavity and herpes simplex in the oral and pharyngeal cavity.
Pharmaceutical composition containing ambroxol or one of the pharmacologically acceptable salts thereof and one or more active substances selected from among the antiseptics, vitamins, corticoids, antiphlogistics, antibiotics, antimycotics and proteolytic enzymes.
Pharmaceutical composition containing ambroxol or one of the pharmacologically acceptable salts thereof and one or more active substances selected from the group consisting of lysozyme hydrochloride, dipotassium glycyrrhizinate, ammonium glycyrrhizinate, cetylpyridinium chloride, chlorpheniramine maleate, noscapine, dequalinium chloride, dextromethorphane, phenolphthalinate, potassium guaiacolsulphonate, dl-methylephedrine hydrochloride, chlorhexidine hydrochloride, and potassium cresolsulphonate.
Pharmaceutical composition consisting of ambroxol, bromhexine or the pharmacologically acceptable salts thereof and pharmaceutical excipients thereof.
Pharmaceutical composition according to one of claims 2 to 5, characterised in that the single dose contains 15 to 50 mg ambroxol.
Use of a pharmaceutical composition consisting of ambroxol hydrochloride, a flavouring, a lubricant, a matrix material, a sweetening agent and a polyethyleneglycol for preparing a medicament for the treatment of pain in the oral and/or pharyngeal cavity, selected from among acute sore throat, aphthae, gingivitis, parodontopathies, pressure points caused by prostheses, pain after oro-pharyngeal interventions, lesions on the mucous membrane in the oral and pharyngeal cavity and herpes simplex in the oral and pharyngeal cavity.
Use of a suckable tablet containing ambroxol based on sugar alcohols as the matrix material, characterised in that it contains a pharmaceutically acceptable layered silicate and a polyethyleneglycol, optionally together with other pharmaceutical excipients, taste or flavouring agents for treating pain in the oral and/or pharyngeal cavity, selected from among acute sore throat, aphthae, gingivitis, parodontopathies, pressure points caused by prostheses, pain after oro-pharyngeal interventions, lesions on the mucous membrane in the oral and pharyngeal cavity and herpes simplex in the oral and pharyngeal cavity.
Dependencies are inferred from the claim text.