Method for linking nucleic acids and/or glycosaminoglycans to polar/hydrophilic materials
AssigneeAngiomed GmbH & Co. Medizintechnik KG
InventorsAntonius H M S M Van Kuppevelt, Jacobus Henricus Veerkamp, Thiemo Arnim Blank
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Abstract
The invention relates to a method for linking nucleic acid and/or glycosaminoglycan or glycosaminoglycan mimetics to a polar/hydrophilic material, characterized by contacting a nucleic acid and/or glycosaminoglycan and a polar/hydrophilic material with each other in the presence of a solution being 20 to 100 percent saturated with a non-chaotropic salt and removing said solution from the nucleic acid and/or glycosaminoglycan—polar/hydrophilic material.
Claims20
Method for linking nucleic acid and/or glycosaminoglycan or glycosaminoglycan mimetics to a polar/hydrophilic material, characterized by contacting a nucleic acid and/or glycosaminoglycan and a polar/hydrophilic material with each other in the presence of a solution being 20 to 100 percent saturated with a non-chaotropic salt and removing said solution from the nucleic acid and/or glycosaminoglycan—polar/hydrophilic material.
Method according to any of claims 1 to 11, characterized in that the glycosaminoglycan is heparin and/or heparan sulfate.
Dependencies are inferred from the claim text.