Galenical formulations
OwnerGerd Fricker, Barbara Haeberlin +2inventors
InventorsGerd Fricker, Barbara Haeberlin, Armin Meinzer, Jacky Vonderscher
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Abstract
A pharmaceutical composition containing macrolide, e.g. a rapamycin compound in an emulsion preconcentrate or microemulsion preconcentrate for oral administration. The carrier medium for the rapamycin compound includes a hydrophilic phase, a lipophilic phase and a surfactant. The composition is stable and provides high absorption efficiency.
Claims9
A pharmaceutical composition comprising a macrolide and a carrier medium comprising a hydrophilic phase, a lipophilic phase and a surfactant.
An microemulsion preconcentrate carrier medium for an orally administrable active agent other than a cyclosporin which comprises
- i) a reaction product of a castor oil and ethylene oxide,
- ii) a transesterification product of a vegetable oil and glycerol comprising predominantly linoleic acid or oleic acid, mono-, di- and triglycerides or a polyoxyalkylated vegetable oil,
- iii) 1,2 propylene glycol and
- iv) ethanol.
Dependencies are inferred from the claim text.