Mucin-related tumor marker
OwnerHuei-Mei Chen, Cynthia D. Honchell +1inventors
InventorsHuei-Mei Chen, Cynthia D. Honchell, Y. Tom Tang
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Abstract
The invention provides a cDNA which encodes a MRTM. It also provides for the use of the cDNA, fragments, variants, and complements thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of cancer, particularly breast cancer. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
Claims20
An isolated cDNA comprising a nucleic acid sequence encoding a protein having the amino acid sequence of SEQ ID NO:
- 1, or the complement thereof.
An isolated cDNA comprising a nucleic acid sequence selected from:
- a) SEQ ID NO:2 or the complement thereof;
- b) a fragment of SEQ ID NO:2 selected from SEQ ID NOs:3-18 or the complement thereof;
- and
- c) a naturally occurring variant of SEQ ID NO:2 having at least 90% sequence identity to SEQ ID NO:2, or the complement thereof.
Dependencies are inferred from the claim text.