Method and device for recognition of a target molecule by means of molecularly imprinted polymers
OwnerBorje Sellergren, Beate Dirioninventors
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Abstract
The invention relates to a method for the preparation of different molecularly imprinted polzmers for recognition of a target molecule by providing particles, frits or monoliths having initiator confined to the surface thereof in separate compartments, adding different monomer mixtures that may contain a template molecule to each compartment, polymerising said mixtures and finally removing the template and excess monomer(S) from the compartments. The invention also relates to a device containing different molecularly imprinted polymers for recognition of a target molecule.
Claims10
A screening method for simultaneous preparation of different molecularly imprinted polymers and flow through mode assessment of the recognition of at least one target molecule,
- characterized by
- a) providing particles, frits or monoliths having initiator confined to the surface thereof in separate compartments;
- b) adding different monomer mixtures that may contain a template molecule to each compartment;
- c) polymerising said mixtures;
- d) removing the template and excess monomer(s) from the compartments;
- e) adding said target molecule(s) to the compartments;
- and
- f) evaluating the recognition of said target molecule(s) by the molecularly imprinted polymers in the compartments, in flow through mode.
Dependencies are inferred from the claim text.