Back to results
US 2003/0166246 A1Published application
Human aspartic proteases
AssigneeIncyte Genomics, Inc.
InventorsHong Xu, Sandra A. Bruno, Laura A. Elsenboss, Michael Fogliano, Victoria L. Cohan, Olga Bandman
Life of this patent
Estimating the term…
Abstract
The invention provides human aspartic proteases (NHAP) and polynucleotides which identify and encode NHAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NHAP.
Claims55
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of:
- a) a polypeptide comprising an amino acid sequence of SEQ ID NO:1 or SEQ ID NO:3,
- b) a naturally occurring polypeptide comprising an amino acid sequence at least 90% identical to an amino acid sequence of SEQ ID NO:1 or SEQ ID NO:3,
- c) a biologically active fragment of a), and
- d) an immunogenic fragment of a).
1 more element
An isolated polynucleotide comprising a sequence selected from the group consisting of:
- a) a polynucleotide comprising a polynucleotide sequence of SEQ ID NO:2 or SEQ ID NO:4,
- b) a naturally occurring polynucleotide comprising a polynucleotide sequence at least 90% identical to a polynucleotide sequence of SEQ ID NO:2 or SEQ ID NO:4,
- c) a polynucleotide having a sequence complementary to a polynucleotide of a),
- d) a polynucleotide having a sequence complementary to a polynucleotide of b) and e) an RNA equivalent of a)-d).
1 more element
Dependencies are inferred from the claim text.