Back to results
US 2003/0166216 A1Published application
Human checkpoint kinase
AssigneeIncyte Genomics, Inc.
InventorsStephen Green, Andrea Georgina King, Olga Bandman, Susan G. Stuart
Life of this patent
Estimating the term…
Abstract
The invention provides a human checkpoint kinase (hChk1) and polynucleotides which identify and encode hChk1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of hChk1.
Claims57
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of:
- a) a polypeptide comprising an amino acid sequence of SEQ ID NO:1,
- b) a naturally occurring polypeptide comprising an amino acid sequence at least 90% identical to an amino acid sequence of SEQ ID NO:1,
- c) a biologically active fragment of a polypeptide having an amino acid sequence of SEQ ID NO:1, and
- d) an immunogenic fragment of a polypeptide having an amino acid sequence of SEQ ID NO:1.
1 more element
An isolated polynucleotide comprising a sequence selected from the group consisting of:
- a) a polynucleotide comprising a polynucleotide sequence of SEQ ID NO:2,
- b) a naturally occurring polynucleotide comprising a polynucleotide sequence at least 90% identical to a polynucleotide sequence of SEQ ID NO:2,
- c) a polynucleotide having a sequence complementary to a polynucleotide of a),
- d) a polynucleotide having a sequence complementary to a polynucleotide of b) and
- e) an RNA equivalent of a)-d).
2 more elements
Dependencies are inferred from the claim text.