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US 2003/0166178 A1Published application
Process for the production of enantiomer-enriched alpha-substituted carboxylic acids
AssigneeDegussa AG
InventorsOliver May, Christoph Syldatk, Oliver Vielhauer, Markus Werner
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Abstract
The present invention provides enzymatic processes for the production of enantiomer-enriched u-substituted carboxylic acids.
Claims22
A process for the production of an enantiomer-enriched α-substituted carboxylic acid comprising
- a) contacting a compound of formula (I) with a hydantoinase
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- wherein, X is O, S, or CH2, and R is an enzyme-reactive organic residue, to form a product of formula (II)
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- wherein X and R are as defined above;
- and
- b) contacting the product of formula (ii) with a carbamoylase:
4 more elements
A process for the production of an enantiomer-enriched α-substituted carboxylic acid comprising contacting a carbamoylase with a compound of formula (II)
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- wherein X is O, S, or CH2, and R is an enzyme-reactive organic residue.
Dependencies are inferred from the claim text.