Thermotoga neapolitana xylose isomerase polypeptides and nucleic acids encoding same
AssigneeBoard of Trustees of Michigan State University
InventorsJ. Gregory Zeikus, Dinlaka Sriprapundh, Claire Vieille
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Abstract
The present invention provides novel isolated polynucleotides encoding a novel xylose isomerases capable of catalyzing the conversion of glucose to fructose and nucleic acids encoding for such isomerase. The present invention also provides a method of producing the xylose isomerase enzymes employing DNA encoding for the enzymes, plasmids containing the DNA, and bacteria into which the plasmids have been inserted and which produce the enzymes.
Claims43
A purified polypeptide comprising an amino acid sequence at least 80% identical to amino acids 2-444 of a sequence selected from the group consisting of SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:
- 8, SEQ ID NO:
- 10 and SEQ ID NO:11.
A purified polypeptide comprising an amino acid sequence at least 95% identical to amino acids 2-444 of a sequence selected from the group consisting of SEQ ID NO:4, SEQ ID NO:6, SEQ ID NO:8, SEQ ID NO:10 and SEQ ID NO:ll, wherein the polypeptide catalyzes the conversion of glucose to fructose.
A purified polypeptide comprising amino acids 2-444 of SEQ ID NO:11.
A purified polypeptide consisting of amino acids 2-444 of SEQ ID NO:
- 11.
Dependencies are inferred from the claim text.