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AssigneeMerck & Co., Inc.
InventorsJoseph P. Arena, Doris F. Cully, Scott D. Feighner, Andrew D. Howard, Paul A. Liberator, James M. Schaeffer, Leonardus H. T. Van Der Ploeg
Estimating the term…
Human, swine and rat growth hormone secretagogue receptors have been isolated, cloned and sequenced. Growth hormone secretagogue receptors are new members of the G-protein family of receptors. The growth hormone secretagogue receptors may be used to screen and identify compounds which bind to the growth hormone secretagogue receptor. Such compounds may be used in the treatment of conditions which occur when there is a shortage of growth hormone, such as observed in growth hormone deficient children, elderly patients with musculoskeletal impairment and recovering from hip fracture and osteoporosis.
A receptor which is a member of the growth hormone family of receptors, free-from receptor-associated proteins.
Growth hormone secretagogue receptor, free from receptor-associated proteins.
Growth hormone secretagogue related receptor, free from receptor-associated proteins.
Isolated growth hormone secretagogue receptor.
A nucleic acid which encodes a receptor that is a member of the growth hormone secretagogue family of receptors, said nucleic acid being free from associated nucleic acids.
A nucleic acid which encodes a growth hormone secretagogue receptor or a functional equivalent, said nucleic acid being free from associated nucleic acids.
A vector comprising a nucleic acid which encodes a receptor which is a member of the growth hormone secretagogue family of receptors.
A vector comprising a nucleic acid which encodes a growth hormone secretagogue receptor, or a functional equivalent.
A nucleic acid encoding a GPCR clone that belongs to the GHSR family and that hybridizes with a nucleotide which encodes either human, swine or rat GHSR under reduced stringency of hybridization.
Dependencies are inferred from the claim text.