14273 receptor, a novel G-protein coupled receptor
AssigneeMillennium Pharmaceuticals, Inc.
InventorsMaria Alexandra Glucksmann, Fong-Ying Tsai
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AssigneeMillennium Pharmaceuticals, Inc.
InventorsMaria Alexandra Glucksmann, Fong-Ying Tsai
Estimating the term…
The present invention relates to a newly identified receptor belonging to the superfamily of G-protein-coupled receptors. The invention also relates to polynucleotides encoding the receptor. The invention further relates to methods using the receptor polypeptides and polynucleotides as a target for diagnosis and treatment in receptor-mediated disorders, specifically, cardiovascular diseases, including congestive heart failure. The invention further relates to drug-screening methods using the receptor polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the receptor polypeptides and polynucleotides. The invention further relates to procedures for producing the receptor polypeptides and polynucleotides.
An isolated polypeptide having an amino acid sequence selected from the group consisting of:
An isolated nucleic acid molecule having a nucleotide sequence selected from the group consisting of:
An isolated nucleic acid molecule having a nucleotide sequence selected from the group consisting of:
An isolated nucleic acid molecule a polynucleotide having a nucleotide sequence selected from the group consisting of:
Dependencies are inferred from the claim text.