Compositions and methods for the therapy and diagnosis of breast cancer
AssigneeCorixa Corporation
InventorsRaymond L. Houghton, Paul R. Sleath, David H. Persing
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Abstract
Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
Claims10
An isolated polypeptide comprising an amino acid sequence selected from the group consisting of:
- (d) sequences set forth in SEQ ID NO:
- 594-627;
- (e) sequences having at least 70% identity to a sequence set forth in SEQ ID NO:
- 594-627;
- and
- (f) sequences having at least 90% identity to a sequence set forth in SEQ ID NO:
- 594-627.
Dependencies are inferred from the claim text.