Triazine library with linkers
OwnerYoung-Tae Chang, Ho-Sang Moon +1inventors
InventorsYoung-Tae Chang, Ho-Sang Moon, Sonya M. Khersonsky
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Abstract
Triazine linkers can be used as universal small molecule chips for functional proteomics and sensors. These compounds are prepared by making a first building block by adding a first amine by reductive amination of triazine, making a second building block by adding a second amine to cyanuric chloride, and combining the first and second building blocks by aminating the first building block onto one of the chloride positions of the second building block.
Claims16
A trisubstituted triazine library.
A method for preparing a trisubstituted triazine library comprising:
- a. making a first building block by adding a first amine by reductive amination of triazine;
- b. making a second building block by adding a second amine to cyanuric chloride;
- c. combining said first building block with said second building block by aminating the first building block onto one of the chloride positions of the second building block;
- d. reacting a third building block with the combined first and second building blocks to produce a trisubstituted triazine.
Triazine-linker compounds comprising a trisubstituted triazine bonded to a linker.
Dependencies are inferred from the claim text.