Compound, especially marker-dye, on the basis of polymethines
AssigneeDyomics GmbH
InventorsPeter Czerney, Matthias Wenzel, Bernd Schweder, Frank Lehmann
Life of this patent
Estimating the term…
Loading patent…
AssigneeDyomics GmbH
InventorsPeter Czerney, Matthias Wenzel, Bernd Schweder, Frank Lehmann
Estimating the term…
The invention relates to fluorescent dyes (fluorophores) based on polymethines for use in optical measurement and detection procedures, in particular those employing fluorescence, for example in medicine, in pharmacology and in the biological, materials and environmental sciences. The objective was to create fluorophores based on polymethines that have a large Stokes shift, high photostability, long storage life and a high fluorescent quantum yield, and that can be excited in the simplest possible manner by white-light sources or laser radiation in the UV, visible or NIR spectral region. According to the invention dyes on the basis of polymethines having the general formulas I, II and III 1 are employed.
Compound, in particular marker-dye, on the basis of polymethines having the general formulas I-III
Application of the substituted polymethine derivatives having the general formulas I-III as dyes for the optical marking of proteins, nucleic acids, oligomers, DNA, RNA, biological cells, lipids, mono-, oligo- and polysaccharides, ligands, receptors, polymers, pharmaceuticals or polymer particles.
Dependencies are inferred from the claim text.