Haplotypes of the TNFRSF1A gene

A method for haplotyping the tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A) gene of an individual, which comprises determining which of the TNFRSF1A haplotype pairs shown in the table immediately below defines both copies of the individual's TNFRSF1A gene, wherein the determining step comprises identifying the phased sequence of nucleotides present at each of PS1-PS18 on both copies of the individual's TNFRSF1A gene, and wherein each of the TNFRSF1A haplotype pairs consists of first and second haplotypes which comprise first and second sequences of polymorphisms whose positions and identities are set forth in the table immediately below:

• 14 HAPLOTYPE PAIRa PSb PS 12/12 22/22 2/2 22/20 12/10 2/1 22/23 2/11 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/T G/G T/T G/G G/G T/T G/G 2 3409 A/A A/A A/A A/A A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 G/G A/A A/A A/A G/G A/A A/A A/G 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/T C/C 10 12489 C/C T/T C/C T/C C/C C/C T/T C/C 11 12653 G/G G/G G/G G/G G/G G/A G/G G/G 12 14824 G/G A/A A/A A/G G/A A/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/T C/C T/T T/C C/C T/T C/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/19 3/14 12/15 22/8 2/9 3/21 2/15 12/17 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T G/G G/G T/G G/G G/T G/G G/G 2 3409 A/A A/A A/G A/A A/A A/A A/G A/G 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G G/A A/G A/G A/A A/A G/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/T C/C C/C C/C C/C C/C C/T 7 11998 G/G G/G G/G G/A G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/C T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C C/C C/C T/C C/C C/T C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/G G/A A/G A/A A/A A/A G/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/T T/T T/C T/T C/T T/C C/C T/C 16 15529 G/A G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/21 22/3 22/25 12/25 12/24 12/13 3/16 22/16 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T T/G T/T G/T G/T G/G G/G T/G 2 3409 A/A A/A A/A A/A A/A A/A A/G A/G 3 3438 C/C C/C C/G C/G C/C C/C C/C C/C 4 3603 A/A A/A A/A G/A G/G G/G A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/T T/C T/T C/T C/T C/T C/C T/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A G/A G/A G/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/C T/T T/T T/T T/T T/T T/T T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 3/27 22/10 2/16 2/26 22/11 12/7 22/2 22/18 NUMBER POSITIONc G/T G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/G G/G G/T T/G G/G T/G T/T 2 3409 A/G A/A A/G A/G A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G A/A A/A A/G G/A A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/A 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C T/C C/C C/C T/C C/C T/C T/T 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A A/A A/A G/G A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/C C/T C/C T/T T/T T/C T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/A G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 22/12 12/5 12/3 12/2 14/6 16/4 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G 1 3102 T/G G/G G/G G/G G/G G/G 2 3409 A/A A/A A/A A/A A/A G/A 3 3438 C/C C/C C/C C/C C/C C/C 4 3603 A/G G/A G/A G/A G/A A/A 5 4054 G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C T/C C/C 7 11998 G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C 10 12489 T/C C/C C/C C/C C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G 12 14824 A/G G/A G/A G/A G/G A/A 13 14990 C/C C/T C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/T 15 15093 T/T T/C T/T T/C T/C T/C 16 15529 G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G 18 16165 aHaplotype pairs are represented as 1st haplotype/2nd haplotype;
• with alleles of each haplotype shown 5′ to 3′ as 1st polymorphism/2nd polymorphism in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1.

A method for predicting a haplotype pair for the tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A) gene of an individual comprising:

• (a) identifying a TNFRSF1A genotype for the individual, wherein the genotype comprises the nucleotide pair at two or more polymorphic sites (PS) selected from the group consisting of PS1, PS4, PS12, PS14, PS15, PS17 and PS18, wherein the selected PS have the position and alternative alleles shown in SEQ ID NO:
• 1;
• (b) comparing the genotype to the haplotype pair data set forth in the table immediately below;
• and
• (c) determining which haplotype pair is consistent with the genotype of the individual and with the haplotype pair data
• 15 HAPLOTYPE PAIRa PSb PS 12/12 22/22 2/2 22/20 12/10 2/1 22/23 2/11 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/T G/G T/T G/G G/G T/T G/G 2 3409 A/A A/A A/A A/A A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 G/G A/A A/A A/A G/G A/A A/A A/G 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/T C/C 10 12489 C/C T/T C/C T/C C/C C/C T/T C/C 11 12653 G/G G/G G/G G/G G/G G/A G/G G/G 12 14824 G/G A/A A/A A/G G/A A/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/T C/C T/T T/C C/C T/T C/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/19 3/14 12/15 22/8 2/9 3/21 2/15 12/17 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T G/G G/G T/G G/G G/T G/G G/G 2 3409 A/A A/A A/G A/A A/A A/A A/G A/G 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G G/A A/G A/G A/A A/A G/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/T C/C C/C C/C C/C C/C C/T 7 11998 G/G G/G G/G G/A G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/C T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C C/C C/C T/C C/C C/T C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/G G/A A/G A/A A/A A/A G/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/T T/T T/C T/T C/T T/C C/C T/C 16 15529 G/A G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/21 22/3 22/25 12/25 12/24 12/13 3/16 22/16 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T T/G T/T G/T G/T G/G G/G T/G 2 3409 A/A A/A A/A A/A A/A A/A A/G A/G 3 3438 C/C C/C C/G C/G C/C C/C C/C C/C 4 3603 A/A A/A A/A G/A G/G G/G A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/T T/C T/T C/T C/T C/T C/C T/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A G/A G/A G/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/C T/T T/T T/T T/T T/T T/T T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 3/27 22/10 2/16 2/26 22/11 12/7 22/2 22/18 NUMBER POSITIONc G/T G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/G G/G G/T T/G G/G T/G T/T 2 3409 A/G A/A A/G A/G A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G A/A A/A A/G G/A A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/A 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C T/C C/C C/C T/C C/C T/C T/T 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A A/A A/A G/G A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/C C/T C/C T/T T/T T/C T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/A G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 22/12 12/5 12/3 12/2 14/6 16/4 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G 1 3102 T/G G/G G/G G/G G/G G/G 2 3409 A/A A/A A/A A/A A/A G/A 3 3438 C/C C/C C/C C/C C/C C/C 4 3603 A/G G/A G/A G/A G/A A/A 5 4054 G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C T/C C/C 7 11998 G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C 10 12489 T/C C/C C/C C/C C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G 12 14824 A/G G/A G/A G/A G/G A/A 13 14990 C/C C/T C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/T 15 15093 T/T T/C T/T T/C T/C T/C 16 15529 G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G 18 16165 aHaplotype pairs are represented as 1st haplotype/2nd haplotype;
• with alleles of each haplotype shown 5′ to 3′ as 1st polymorphism/2nd polymorphism in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1.

A method for identifying an association between a trait and at least one haplotype or haplotype pair of the tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A) gene which comprises comparing the frequency of the haplotype or haplotype pair in a population exhibiting the trait with the frequency of the haplotype or haplotype pair in a reference population, wherein the haplotype is selected from haplotypes 1-27 shown in the table presented immediately below, wherein each of the haplotypes comprises a sequence of polymorphisms whose positions and identities are set forth in the table immediately below:

• 16 HAPLOTYPE NUMBERa PSb PS 1 2 3 4 5 6 7 8 9 10 NUMBER POSITIONc G G G G G G G G G G 1 3102 G G G G G G G G G G 2 3409 A A A A A A A A A A 3 3438 C C C C C C C C C C 4 3603 A A A A A A A G G G 5 4054 G G G G G G G G G G 6 4082 C C C C C C C C C C 7 11998 G G G G G G G A G G 8 12356 T T T T T T T T C T 9 12397 C C C C C C C C C C 10 12489 C C C C C C C C C C 11 12653 A G G G G G G G G G 12 14824 A A A A A G G G A A 13 14990 C C C C T C C C C C 14 15089 C C C T C C C C C C 15 15093 C C T C C C T T T C 16 15529 G G G G G G G G G G 17 15932 G G G G G G G G G G 18 16165 HAPLOTYPE NUMBERa PSb PS 11 12 13 14 15 16 17 18 19 20 NUMBER POSITIONc G G G G G G G G G G 1 3102 G G G G G G G T T T 2 3409 A A A A G G G A A A 3 3438 C C C C C C C C C C 4 3603 G G G G A A A A A A 5 4054 G G G G G G G A G G 6 4082 C C C T C C T C C C 7 11998 G G G G G G G G G G 8 12356 T T T T T T T T T T 9 12397 C C C C C C C C C C 10 12489 C C T C C C C T C C 11 12653 G G G G G G G G G G 12 14824 A G A G A A A A A G 13 14990 C C C C C C C C C C 14 15089 C C C C C C C C C C 15 15093 T T T T C T C T T T 16 15529 G G G G G G G G A G 17 15932 G G G G G G G G G G 18 16165 HAPLOTYPE NUMBERa PSb PS 21 22 23 24 25 26 27 NUMBER POSITIONc G G G G G G T 1 3102 T T T T T T G 2 3409 A A A A A G G 3 3438 C C C C G C C 4 3603 A A A G A A A 5 4054 G G G G G G G 6 4082 C C C C C C C 7 11998 G G G G G G G 8 12356 T T T T T T T 9 12397 C C T C C C C 10 12489 T T T T T C C 11 12653 G G G G G G G 12 14824 A A A A A A A 13 14990 C C C C C C C 14 15089 C C C C C C C 15 15093 C T T T T C T 16 15529 G G G G G G G 17 15932 G G G G G G A 18 16165 aAlleles for haplotypes are presented 5′ to 3′ in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1;
• and wherein the haplotype pair is selected from the haplotype pairs shown in the table immediately below, wherein each of the TNFRSF1A haplotype pairs consists of first and second haplotypes which comprise first and second sequences of polymorphisms whose positions and identities are set forth in the table immediately below:
• 17 HAPLOTYPE PAIRa PSb PS 12/12 22/22 2/2 22/20 12/10 2/1 22/23 2/11 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/T G/G T/T G/G G/G T/T G/G 2 3409 A/A A/A A/A A/A A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 G/G A/A A/A A/A G/G A/A A/A A/G 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/T C/C 10 12489 C/C T/T C/C T/C C/C C/C T/T C/C 11 12653 G/G G/G G/G G/G G/G G/A G/G G/G 12 14824 G/G A/A A/A A/G G/A A/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/T C/C T/T T/C C/C T/T C/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/19 3/14 12/15 22/8 2/9 3/21 2/15 12/17 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T G/G G/G T/G G/G G/T G/G G/G 2 3409 A/A A/A A/G A/A A/A A/A A/G A/G 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G G/A A/G A/G A/A A/A G/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/T C/C C/C C/C C/C C/C C/T 7 11998 G/G G/G G/G G/A G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/C T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C C/C C/C T/C C/C C/T C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/G G/A A/G A/A A/A A/A G/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/T T/T T/C T/T C/T T/C C/C T/C 16 15529 G/A G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/21 22/3 22/25 12/25 12/24 12/13 3/16 22/16 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T T/G T/T G/T G/T G/G G/G T/G 2 3409 A/A A/A A/A A/A A/A A/A A/G A/G 3 3438 C/C C/C C/G C/G C/C C/C C/C C/C 4 3603 A/A A/A A/A G/A G/G G/G A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/T T/C T/T C/T C/T C/T C/C T/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A G/A G/A G/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/C T/T T/T T/T T/T T/T T/T T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 3/27 22/10 2/16 2/26 22/11 12/7 22/2 22/18 NUMBER POSITIONc G/T G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/G G/G G/T T/G G/G T/G T/T 2 3409 A/G A/A A/G A/G A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G A/A A/A A/G G/A A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/A 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C T/C C/C C/C T/C C/C T/C T/T 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A A/A A/A G/G A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/C C/T C/C T/T T/T T/C T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/A G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 22/12 12/5 12/3 12/2 14/6 16/4 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G 1 3102 T/G G/G G/G G/G G/G G/G 2 3409 A/A A/A A/A A/A A/A G/A 3 3438 C/C C/C C/C C/C C/C C/C 4 3603 A/G G/A G/A G/A G/A A/A 5 4054 G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C T/C C/C 7 11998 G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C 10 12489 T/C C/C C/C C/C C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G 12 14824 A/G G/A G/A G/A G/G A/A 13 14990 C/C C/T C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/T 15 15093 T/T T/C T/T T/C T/C T/C 16 15529 G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G 18 16165 aHaplotype pairs are represented as 1st haplotype/2nd haplotype;
• with alleles of each haplotype shown 5′ to 3′ as 1st polymorphism/2nd polymorphism in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1;
• wherein a higher frequency of the haplotype or haplotype pair in the trait population than in the reference population indicates the trait is associated with the haplotype or haplotype pair.

An isolated polynucleotide comprising a nucleotide sequence selected from the group consisting of:

• (a) a first nucleotide sequence which comprises a tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A) isogene, wherein the TNFRSF1A isogene is selected from the group consisting of isogenes 1-27 shown in the table immediately below and wherein each of the isogenes comprises the regions of SEQ ID NO:
• 1 shown in the table immediately below and wherein each of the isogenes 1-27 is further defined by the corresponding sequence of polymorphisms whose positions and identities are set forth in the table immediately below;
• and
• 18 ISOGENE NUMBERa PSb PS SEQ ID REGION 1 2 3 4 5 6 7 8 9 10 NUMBER POSITIONc NO. EXAMINEDd G G G G G G G G G G 1 3102 1 2920-4210 G G G G G G G G G G 2 3409 1 2920-4210 A A A A A A A A A A 3 3438 1 2920-4210 C C C C C C C C C C 4 3603 1 2920-4210 A A A A A A A G G G 5 4054 1 2920-4210 G G G G G G G G G G 6 4082 1 2920-4210 C C C C C C C C C C 7 11998 1 11417-12926 G G G G G G G A G G 8 12356 1 11417-12926 T T T T T T T T C T 9 12397 1 11417-12926 C C C C C C C C C C 10 12489 1 11417-12926 C C C C C C C C C C 11 12653 1 11417-12926 A G G G G G G G G G 12 14824 1 14634-16768 A A A A A G G G A A 13 14990 1 14634-16768 C C C C T C C C C C 14 15089 1 14634-16768 C C C T C C C C C C 15 15093 1 14634-16768 C C T C C C T T T C 16 15529 1 14634-16768 G G G G G G G G G G 17 15932 1 14634-16768 G G G G G G G G G G 18 16165 1 14634-16768 ISOGENE NUMBERa PSb PS SEQ ID REGION 11 12 13 14 15 16 17 18 19 20 NUMBER POSITIONc NO. EXAMINEDd G G G G G G G G G G 1 3102 1 2920-4210 G G G G G G G T T T 2 3409 1 2920-4210 A A A A G G G A A A 3 3438 1 2920-4210 C C C C C C C C C C 4 3603 1 2920-4210 G G G G A A A A A A 5 4054 1 2920-4210 G G G G G G G A G G 6 4082 1 2920-4210 C C C T C C T C C C 7 11998 1 11417-12926 G G G G G G G G G G 8 12356 1 11417-12926 T T T T T T T T T T 9 12397 1 11417-12926 C C C C C C C C C C 10 12489 1 11417-12926 C C T C C C C T C C 11 12653 1 11417-12926 G G G G G G G G G G 12 14824 1 14634-16768 A G A G A A A A A G 13 14990 1 14634-16768 C C C C C C C C C C 14 15089 1 14634-16768 C C C C C C C C C C 15 15093 1 14634-16768 T T T T C T C T T T 16 15529 1 14634-16768 G G G G G G G G A G 17 15932 1 14634-16768 G G G G G G G G G G 18 16165 1 14634-16768 ISOGENE NUMBERa PSb PS SEQ ID REGION 21 22 23 24 25 26 27 NUMBER POSITIONc NO. EXAMINEDd G G G G G G T 1 3102 1 2920-4210 T T T T T T G 2 3409 1 2920-4210 A A A A A G G 3 3438 1 2920-4210 C C C C G C C 4 3603 1 2920-4210 A A A G A A A 5 4054 1 2920-4210 G G G G G G G 6 4082 1 2920-4210 C C C C C C C 7 11998 1 11417-12926 G G G G G G G 8 12356 1 11417-12926 T T T T T T T 9 12397 1 11417-12926 C C T C C C C 10 12489 1 11417-12926 T T T T T C C 11 12653 1 11417-12926 G G G G G G G 12 14824 1 14634-16768 A A A A A A A 13 14990 1 14634-16768 C C C C C C C 14 15089 1 14634-16768 C C C C C C C 15 15093 1 14634-16768 C T T T T C T 16 15529 1 14634-16768 G G G G G G G 17 15932 1 14634-16768 G G G G G G A 18 16165 1 14634-16768 aAlleles for isogenes are presented 5′ to 3′ in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1;
• dRegion examined represents the nucleotide positions defining the start and stop positions within SEQ ID NO:
• 1 of the sequenced region.
• (b) a second nucleotide sequence which is complementary to the first nucleotide sequence.

An isolated fragment of a tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A) isogene, wherein the fragment comprises at least 10 nucleotides in one of the regions of SEQ ID NO:

• 1 shown in the table immediately below and wherein the fragment comprises one or more polymorphisms selected from the group consisting of thymine at PS1, guanine at PS4, adenine at PS12, thymine at PS14, thymine at PS15, adenine at PS17 and adenine at PS18, wherein the selected polymorphism has the position set forth in the table immediately below:
• 19 ISOGENE NUMBERa PSb PS SEQ ID REGION 1 2 3 4 5 6 7 8 9 10 NUMBER POSITIONc NO. EXAMINEDd G G G G G G G G G G 1 3102 1 2920-4210 G G G G G G G G G G 2 3409 1 2920-4210 A A A A A A A A A A 3 3438 1 2920-4210 C C C C C C C C C C 4 3603 1 2920-4210 A A A A A A A G G G 5 4054 1 2920-4210 G G G G G G G G G G 6 4082 1 2920-4210 C C C C C C C C C C 7 11998 1 11417-12926 G G G G G G G A G G 8 12356 1 11417-12926 T T T T T T T T C T 9 12397 1 11417-12926 C C C C C C C C C C 10 12489 1 11417-12926 C C C C C C C C C C 11 12653 1 11417-12926 A G G G G G G G G G 12 14824 1 14634-16768 A A A A A G G G A A 13 14990 1 14634-16768 C C C C T C C C C C 14 15089 1 14634-16768 C C C T C C C C C C 15 15093 1 14634-16768 C C T C C C T T T C 16 15529 1 14634-16768 G G G G G G G G G G 17 15932 1 14634-16768 G G G G G G G G G G 18 16165 1 14634-16768 ISOGENE NUMBERa PSb PS SEQ ID REGION 11 12 13 14 15 16 17 18 19 20 NUMBER POSITIONc NO. EXAMINEDd G G G G G G G G G G 1 3102 1 2920-4210 G G G G G G G T T T 2 3409 1 2920-4210 A A A A G G G A A A 3 3438 1 2920-4210 C C C C C C C C C C 4 3603 1 2920-4210 G G G G A A A A A A 5 4054 1 2920-4210 G G G G G G G A G G 6 4082 1 2920-4210 C C C T C C T C C C 7 11998 1 11417-12926 G G G G G G G G G G 8 12356 1 11417-12926 T T T T T T T T T T 9 12397 1 11417-12926 C C C C C C C C C C 10 12489 1 11417-12926 C C T C C C C T C C 11 12653 1 11417-12926 G G G G G G G G G G 12 14824 1 14634-16768 A G A G A A A A A G 13 14990 1 14634-16768 C C C C C C C C C C 14 15089 1 14634-16768 C C C C C C C C C C 15 15093 1 14634-16768 T T T T C T C T T T 16 15529 1 14634-16768 G G G G G G G G A G 17 15932 1 14634-16768 G G G G G G G G G G 18 16165 1 14634-16768 ISOGENE NUMBERa PSb PS SEQ ID REGION 21 22 23 24 25 26 27 NUMBER POSITIONc NO. EXAMINEDd G G G G G G T 1 3102 1 2920-4210 T T T T T T G 2 3409 1 2920-4210 A A A A A G G 3 3438 1 2920-4210 C C C C G C C 4 3603 1 2920-4210 A A A G A A A 5 4054 1 2920-4210 G G G G G G G 6 4082 1 2920-4210 C C C C C C C 7 11998 1 11417-12926 G G G G G G G 8 12356 1 11417-12926 T T T T T T T 9 12397 1 11417-12926 C C T C C C C 10 12489 1 11417-12926 T T T T T C C 11 12653 1 11417-12926 G G G G G G G 12 14824 1 14634-16768 A A A A A A A 13 14990 1 14634-16768 C C C C C C C 14 15089 1 14634-16768 C C C C C C C 15 15093 1 14634-16768 C T T T T C T 16 15529 1 14634-16768 G G G G G G G 17 15932 1 14634-16768 G G G G G G A 18 16165 1 14634-16768 aAlleles for isogenes are presented 5′ to 3′ in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1;
• dRegion examined represents the nucleotide positions defining the start and stop positions within SEQ ID NO:
• 1 of the sequenced region.

An isolated polynucleotide comprising a TNFRSF1A coding sequence, wherein the coding sequence is selected from the group consisting of 8, 9, 14, 17, and 19 shown in the table immediately below, and wherein each of the coding sequences comprises SEQ ID NO:

• 2, except at each of the polymorphic sites which have the positions in SEQ ID NO:
• 2 and polymorphisms set forth in the table immediately below:
• 20 Isogene Coding Sequence Number PS PS 8 9 14, 17 19 Number Position C C T C 7 224 A G G G 8 362 T C T T 9 403 G G G A 17 935
• ‘Alleles for the isogene coding sequence are presented 5′ to 3′ in each column;
• the numerical portion of the isogene coding sequence number represents the number of the parent full TNFRSF1A isogene;
• bpS =polymorphic site;
• cPosition of PS in SEQ ID NO:
• 2.

33 A computer system for storing and analyzing polymorphism data for the tumor necrosis factor receptor superfamily, member 1A gene, comprising:

• (a) a central processing unit (CPU);
• (b) a communication interface;
• (c) a display device;
• (d) an input device;
• and
• (e) a database containing the polymorphism data;
• wherein the polymorphism data comprises any one or more of the haplotypes set forth in the table immediately below:
• 21 HAPLOTYPE NUMBERa PSb PS 1 2 3 4 5 6 7 8 9 10 NUMBER POSITIONc G G G G G G G G G G 1 3102 G G G G G G G G G G 2 3409 A A A A A A A A A A 3 3438 C C C C C C C C C C 4 3603 A A A A A A A G G G 5 4054 G G G G G G G G G G 6 4082 C C C C C C C C C C 7 11998 G G G G G G G A G G 8 12356 T T T T T T T T C T 9 12397 C C C C C C C C C C 10 12489 C C C C C C C C C C 11 12653 A G G G G G G G G G 12 14824 A A A A A G G G A A 13 14990 C C C C T C C C C C 14 15089 C C C T C C C C C C 15 15093 C C T C C C T T T C 16 15529 G G G G G G G G G G 17 15932 G G G G G G G G G G 18 16165 HAPLOTYPE NUMBERa PSb PS 11 12 13 14 15 16 17 18 19 20 NUMBER POSITIONc G G G G G G G G G G 1 3102 G G G G G G G T T T 2 3409 A A A A G G G A A A 3 3438 C C C C C C C C C C 4 3603 G G G G A A A A A A 5 4054 G G G G G G G A G G 6 4082 C C C T C C T C C C 7 11998 G G G G G G G G G G 8 12356 T T T T T T T T T T 9 12397 C C C C C C C C C C 10 12489 C C T C C C C T C C 11 12653 G G G G G G G G G G 12 14824 A G A G A A A A A G 13 14990 C C C C C C C C C C 14 15089 C C C C C C C C C C 15 15093 T T T T C T C T T T 16 15529 G G G G G G G G A G 17 15932 G G G G G G G G G G 18 16165 HAPLOTYPE NUMBERa PSb PS 21 22 23 24 25 26 27 NUMBER POSITIONc G G G G G G T 1 3102 T T T T T T G 2 3409 A A A A A G G 3 3438 C C C C G C C 4 3603 A A A G A A A 5 4054 G G G G G G G 6 4082 C C C C C C C 7 11998 G G G G G G G 8 12356 T T T T T T T 9 12397 C C T C C C C 10 12489 T T T T T C C 11 12653 G G G G G G G 12 14824 A A A A A A A 13 14990 C C C C C C C 14 15089 C C C C C C C 15 15093 C T T T T C T 16 15529 G G G G G G G 17 15932 G G G G G G A 18 16165 aAlleles for haplotypes are presented 5′ to 3′ in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1;
• the haplotype pairs set forth in the table immediately below:
• 22 HAPLOTYPE PAIRa PSb PS 12/12 22/22 2/2 22/20 12/10 2/1 22/23 2/11 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/T G/G T/T G/G G/G T/T G/G 2 3409 A/A A/A A/A A/A A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 G/G A/A A/A A/A G/G A/A A/A A/G 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/T C/C 10 12489 C/C T/T C/C T/C C/C C/C T/T C/C 11 12653 G/G G/G G/G G/G G/G G/A G/G G/G 12 14824 G/G A/A A/A A/G G/A A/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/T C/C T/T T/C C/C T/T C/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/19 3/14 12/15 22/8 2/9 3/21 2/15 12/17 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T G/G G/G T/G G/G G/T G/G G/G 2 3409 A/A A/A A/G A/A A/A A/A A/G A/G 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G G/A A/G A/G A/A A/A G/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/T C/C C/C C/C C/C C/C C/T 7 11998 G/G G/G G/G G/A G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/C T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C C/C C/C T/C C/C C/T C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/G G/A A/G A/A A/A A/A G/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/T T/T T/C T/T C/T T/C C/C T/C 16 15529 G/A G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 2/21 22/3 22/25 12/25 12/24 12/13 3/16 22/16 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G G/G G/G 1 3102 G/T T/G T/T G/T G/T G/G G/G T/G 2 3409 A/A A/A A/A A/A A/A A/A A/G A/G 3 3438 C/C C/C C/G C/G C/C C/C C/C C/C 4 3603 A/A A/A A/A G/A G/G G/G A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/T T/C T/T C/T C/T C/T C/C T/C 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A G/A G/A G/A A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 C/C T/T T/T T/T T/T T/T T/T T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 3/27 22/10 2/16 2/26 22/11 12/7 22/2 22/18 NUMBER POSITIONc G/T G/G G/G G/G G/G G/G G/G G/G 1 3102 G/G T/G G/G G/T T/G G/G T/G T/T 2 3409 A/G A/A A/G A/G A/A A/A A/A A/A 3 3438 C/C C/C C/C C/C C/C C/C C/C C/C 4 3603 A/A A/G A/A A/A A/G G/A A/A A/A 5 4054 G/G G/G G/G G/G G/G G/G G/G G/A 6 4082 C/C C/C C/C C/C C/C C/C C/C C/C 7 11998 G/G G/G G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C C/C C/C 10 12489 C/C T/C C/C C/C T/C C/C T/C T/T 11 12653 G/G G/G G/G G/G G/G G/G G/G G/G 12 14824 A/A A/A A/A A/A A/A G/G A/A A/A 13 14990 C/C C/C C/C C/C C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/C C/C C/C 15 15093 T/T T/C C/T C/C T/T T/T T/C T/T 16 15529 G/G G/G G/G G/G G/G G/G G/G G/G 17 15932 G/A G/G G/G G/G G/G G/G G/G G/G 18 16165 HAPLOTYPE PAIRa PSb PS 22/12 12/5 12/3 12/2 14/6 16/4 NUMBER POSITIONc G/G G/G G/G G/G G/G G/G 1 3102 T/G G/G G/G G/G G/G G/G 2 3409 A/A A/A A/A A/A A/A G/A 3 3438 C/C C/C C/C C/C C/C C/C 4 3603 A/G G/A G/A G/A G/A A/A 5 4054 G/G G/G G/G G/G G/G G/G 6 4082 C/C C/C C/C C/C T/C C/C 7 11998 G/G G/G G/G G/G G/G G/G 8 12356 T/T T/T T/T T/T T/T T/T 9 12397 C/C C/C C/C C/C C/C C/C 10 12489 T/C C/C C/C C/C C/C C/C 11 12653 G/G G/G G/G G/G G/G G/G 12 14824 A/G G/A G/A G/A G/G A/A 13 14990 C/C C/T C/C C/C C/C C/C 14 15089 C/C C/C C/C C/C C/C C/T 15 15093 T/T T/C T/T T/C T/C T/C 16 15529 G/G G/G G/G G/G G/G G/G 17 15932 G/G G/G G/G G/G G/G G/G 18 16165 aHaplotype pairs are represented as 1st Haplotype/2nd Haplotype;
• with alleles of each haplotype shown 5′ to 3′ as 1st polymorphism/2nd polymorphism in each column;
• cPosition of PS in SEQ ID NO:
• 1;
• and the frequency data in Tables 6 and 7.

A genome anthology for the tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A) gene which comprises two or more TNFRSF1A isogenes selected from the group consisting of isogenes 1-27 shown in the table immediately below, and wherein each of the isogenes comprises the regions of SEQ ID NO:

• 1 shown in the table immediately below and wherein each of the isogenes 1-27 is further defined by the corresponding sequence of polymorphisms whose positions and identities are set forth in the table immediately below:
• 23 ISOGENE NUMBERa PSb PS SEQ ID REGION 1 2 3 4 5 6 7 8 9 10 NUMBER POSITIONc NO. EXAMINEDd G G G G G G G G G G 1 3102 1 2920-4210 G G G G G G G G G G 2 3409 1 2920-4210 A A A A A A A A A A 3 3438 1 2920-4210 C C C C C C C C C C 4 3603 1 2920-4210 A A A A A A A G G G 5 4054 1 2920-4210 G G G G G G G G G G 6 4082 1 2920-4210 C C C C C C C C C C 7 11998 1 11417-12926 G G G G G G G A G G 8 12356 1 11417-12926 T T T T T T T T C T 9 12397 1 11417-12926 C C C C C C C C C C 10 12489 1 11417-12926 C C C C C C C C C C 11 12653 1 11417-12926 A G G G G G G G G G 12 14824 1 14634-16768 A A A A A G G G A A 13 14990 1 14634-16768 C C C C T C C C C C 14 15089 1 14634-16768 C C C T C C C C C C 15 15093 1 14634-16768 C C T C C C T T T C 16 15529 1 14634-16768 G G G G G G G G G G 17 15932 1 14634-16768 G G G G G G G G G G 18 16165 1 14634-16768 ISOGENE NUMBERa PSb PS SEQ ID REGION 11 12 13 14 15 16 17 18 19 20 NUMBER POSITIONc NO. EXAMINEDd G G G G G G G G G G 1 3102 1 2920-4210 G G G G G G G T T T 2 3409 1 2920-4210 A A A A G G G A A A 3 3438 1 2920-4210 C C C C C C C C C C 4 3603 1 2920-4210 G G G G A A A A A A 5 4054 1 2920-4210 G G G G G G G A G G 6 4082 1 2920-4210 C C C T C C T C C C 7 11998 1 11417-12926 G G G G G G G G G G 8 12356 1 11417-12926 T T T T T T T T T T 9 12397 1 11417-12926 C C C C C C C C C C 10 12489 1 11417-12926 C C T C C C C T C C 11 12653 1 11417-12926 G G G G G G G G G G 12 14824 1 14634-16768 A G A G A A A A A G 13 14990 1 14634-16768 C C C C C C C C C C 14 15089 1 14634-16768 C C C C C C C C C C 15 15093 1 14634-16768 T T T T C T C T T T 16 15529 1 14634-16768 G G G G G G G G A G 17 15932 1 14634-16768 C G G G G G G G G G 18 16165 1 14634-16768 ISOGENE NUMBERa PSb PS SEQ ID REGION 21 22 23 24 25 26 27 NUMBER POSITIONc NO. EXAMINEDd G G G G G G T 1 3102 1 2920-4210 T T T T T T G 2 3409 1 2920-4210 A A A A A G G 3 3438 1 2920-4210 C C C C G C C 4 3603 1 2920-4210 A A A G A A A 5 4054 1 2920-4210 G G G G G G G 6 4082 1 2920-4210 C C C C C C C 7 11998 1 11417-12926 G G G G G G G 8 12356 1 11417-12926 T T T T T T T 9 12397 1 11417-12926 C C T C C C C 10 12489 1 11417-12926 T T T T T C C 11 12653 1 11417-12926 G G G G G G G 12 14824 1 14634-16768 A A A A A A A 13 14990 1 14634-16768 C C C C C C C 14 15089 1 14634-16768 C C C C C C C 15 15093 1 14634-16768 C T T T T C T 16 15529 1 14634-16768 G G G G G G G 17 15932 1 14634-16768 G G G G G G A 18 16165 1 14634-16768 aAlleles for isogenes are presented 5′ to 3′ in each column;
• bPS = polymorphic site;
• cPosition of PS in SEQ ID NO:
• 1;
• dRegion examined represents the nucleotide positions defining the start and stop positions within SEQ ID NO:
• 1 of the sequenced region.