Novel compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use
AssigneeBradley Pharmaceuticals, Inc.
InventorsDileep Bhagwat, Bradley P. Glassman, Daniel Glassman
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Abstract
Topical compositions which include urea and an antimicrobial agent, particularly sulfacetamide or metronidazole, are described. Sulfacetamide compositions further including sulfur are also described. Methods for treating dermatological disorders using the compositions are also described.
Claims39
A topical composition for the treatment of dermatological disorders comprising:
- (a) a dermatologically effective amount of an antimicrobial agent;
- (b) a dermatologically effective amount of urea;
- (c) a dermatologically effective amount of an anti-inflammatory agent;
- and
- (d) a dermatologically acceptable carrier.
A topical composition for treatment of dermatological disorders comprising:
- (a) a dermatologically effective amount of sulfacetamide or a salt thereof;
- (b) a dermatologically effective amount of urea;
- (c) a dermatologically effective amount of gamma tocopherol;
- and;
- (d) a dermatologically acceptable carrier.
A topical composition for the treatment of dermatological disorders comprising:
- (a) a dermatologically effective amount of metronidazole or a pharmaceutically acceptable salt thereof;
- (b) a dermatologically effective amount of urea;
- and
- (c) a dermatologically acceptable carrier.
A method for improving the effectiveness of topical metronidazole in the treatment of susceptible dermatological conditions of the skin comprising administering before, after or with the administration of a topical dose of metronidazole to the affected area of a patient in need thereof a composition comprising urea and the balance being dermatologically acceptable excipients.
Dependencies are inferred from the claim text.