Novel fibronectin-binding protein
OwnerBengt Guss, Karin Jacobsson +2inventors
InventorsBengt Guss, Karin Jacobsson, Lars Frykberg, Hans Lindmark
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Abstract
The present invention is concerned with a novel fibronectin-binding protein of Streptococcus equi, to a DNA fragment encoding this protein, to host cells and vectors containing said DNA fragment and to methods to produce said protein based on recombinant DNA technology. The invention is also related to use of said protein in the preparation of a vaccine, to a vaccine containing said protein, to antibodies specific for said protein and to polyvalent antisera containing such antibodies.
Claims21
An isolated protein, an analog thereof, or a fragment thereof, having an amino acid sequence encoded by a nucleic acid sequence, that can be isolated from and forms a portion of the genomes of Streptococcus equi, which protein can be expressed from said nucleic acid sequence and which protein binds specifically to mammal fibronectin, provided that the amino acid sequence shown in SEQ ID NO. 18 is excluded.
An isolated protein specifically binding to fibronectin and having an amino acid sequence as shown in SEQ. ID. NO. 1, or an analog or fragment thereof.
Dependencies are inferred from the claim text.