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US 2003/0165513 A1Published application
Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
AssigneeImmunotope, Inc.
InventorsVenky Ramakrishna, Mark M. Ross, Ramila Philip
Life of this patent
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Abstract
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as ovarian carcinoma. The invention discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a CTL response against cancer.
Claims28
An immunogen comprising an isolated polypeptide whose amino acid sequence comprises at least one epitopic peptide selected from the group consisting of SEQ ID NOS:
- 1-20 and wherein when the epitopic peptide is one of SEQ ID NO:
- 17-20 said polypeptide does not include MAGE 4 or MFG-E8 proteins.
An immunogen comprising a member selected from the group consisting of Mage D protein and an immunologically active fragment of Mage D protein.
Dependencies are inferred from the claim text.