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US 2003/0164449 A1Published application
Method for analysing enzyme-catalysed reactions using maldi-tof mass spectrometry
AssigneeBASF SE
InventorsElmar Heinzle, Min-Jung Kang, Andreas Tholey, Klaus Hollemeyer, Bernhard Hauer
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Abstract
A process is described for analyzing enzyme-catalyzed conversions of nonpolymeric substrates to nonpolymeric products with the aid of MALDI-TOF mass spectrometry, preferably in the presence of an internal standard on a specific carrier material.
Claims15
A process for analyzing enzyme-catalyzed conversions of nonpolymeric substrates to nonpolymeric products, which comprises analyzing the substrate and product of the enzyme-catalyzed conversion with the aid of MALDI-TOF mass spectrometry, with said process including the following steps:
- a) enzyme-catalyzed conversion of a nonpolymeric substrate to a nonpolymeric product,
- b) analysis of the substrate or product or of the substrate and product during or after the enzyme-catalyzed conversion (a) using MALDI-TOF mass spectrometry.
Dependencies are inferred from the claim text.