Process for producing paroxetine salts substantially free from organic solvents
AssigneeAsahi Glass Company, Limited
InventorsShu-Zhong Wang, Erika Saito, Naoya Shimokawa
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Abstract
A paroxetine salt free from an organic solvent is produced by substantially and safely removing the organic solvents from paroxetine hydrochloride. A process for producing a paroxetine salt, which comprises neutralizing paroxetine hydrochloride containing an organic solvent into paroxetine, then forming a salt of paroxetine with an acid other than hydrochloric acid, and crystallizing the salt from an organic solvent.
Claims12
A process for producing a paroxetine salt substantially free from an organic solvent, which comprises neutralizing paroxetine hydrochloride containing an organic solvent into paroxetine, then forming a salt of paroxetine with an acid other than hydrochloric acid, and crystallizing the salt from an organic solvent to give a salt other than paroxetine hydrochloride.
Crystalline paroxetine acetate substantially free from an organic solvent.
Dependencies are inferred from the claim text.