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US 2003/0158386 A1Published application
Interleukin-15 receptors
AssigneeImmunex Corporation
InventorsDirk M. Anderson, Judith G. Giri
Life of this patent
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Abstract
There are disclosed Interleukin-15 Receptor (IL-15R) proteins, DNAs and expression vectors encoding IL-15R, and processes for producing IL-15R as products of recombinant cell cultures.
Claims18
An isolated DNA encoding an IL-15 receptor (IL-15R), wherein the DNA is selected from the group consisting of:
- (a) a DNA having a nucleotide sequence as set forth in SEQ ID NO:1, nucleotides 91 through 789;
- (b) a DNA having a nucleotide sequence as set forth in SEQ ID NO:6, nucleotides 34 through 753;
- (c) DNAs that hybridize to the DNA sequences of (a) or (b) or their complementary strands under conditions of high stringency, and which encode polypeptides capable of binding IL-15;
- and
- (d) DNAs that, due to degeneracy of the genetic code, encode polypeptides encoded by any of the foregoing DNAs.
2 more elements
Antibodies immunoreactive with mammalian IL-15 receptors.
An antibody according to claim 16 which is a monoclonal antibody.
Dependencies are inferred from the claim text.