Back to results
US 2003/0158376 A1Published application
Relaxin-like factor and methods and uses thereof
AssigneeBAS Medical, Inc.
InventorsChristian Schwabe, Elaine Unemori
Life of this patent
Estimating the term…
Abstract
The present invention relates to a relaxin-like factor, its derivatives or analogs, and uses thereof. The present invention further relates to compositions comprising a relaxin-like factor, its derivatives or analogs, and relaxin wherein such composition exhibits an additive or synergistic effect.
Claims13
Relaxin like factor comprising an A chain and a B chain,
- said A chain having the amino acid sequence:
- Gln-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys or an amino acid sequence truncated by up to about 6 amino acids from the N-terminus and/or by up to 6 amino acids from the C-terminus;
- said B chain having the amino acid sequence:
- Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser or an amino acid sequence truncated by up to 5 amino acids from the N-terminus and/or by up to 5 amino acids from the C-terminus;
- said A and B chains linked by disulfide bonds between A11 and B11 and wherein said relaxin like factor displaces bound relaxin tracer from the receptor to which it is bound.
2 more elements
Dependencies are inferred from the claim text.