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AssigneeKao Corporation
InventorsTadashi Hase, Takatoshi Murase, Hiroyuki Watanabe, Hidehiko Kondo
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Disclosed are a method for activating lipid metabolism in the small intestine epithelium and also a method for promoting accumulation of fatty acids into the small intestine epithelium, each of which features administering an effective amount of a diacylglycerol. Also disclosed are methods for improving various symptoms in diabetes, which have ingesting a diacylglycerol. Ingestion of the diacylglycerol leads to accumulation of the fatty acids in the small intestine. The fatty acids so accumulated promote induction of β-oxidation, thereby not only activating lipid catabolism but also making it difficult to allow lipids to accumulate as triacylglycerols. This series of actions eventually results in development of lowering action for blood remnant-like lipoprotein level and also lowering action for blood leptin level, and hence, lipid metabolism is improved. Further, energy consumption is enhanced by promoting the induction of β-oxidation and activating lipid catabolism.
A method for activating lipid catabolism in the small intestine epithelium, which comprises administering an effective amount of a diacylglycerol.
A method for promoting accumulation of fatty acids into the small intestine epithelium, which comprises administering an effective amount of a diacylglycerol.
A method for inducing expression of a small intestine lipid metabolic gene, which comprises administering an effective amount of a diacylglycerol.
A method for suppressing synthesis of a triacylglycerol in the small intestine epithelium, which comprises administering an effective amount of a diacylglycerol.
A method for promoting energy consumption, which comprises administering an effective amount of a diacylglycerol.
A method for lowering a serum RLP level, which comprises inistering an effective amount of a diacylglycerol.
A method for lowering a serum leptin level, which comprises administering an effective amount of a diacylglycerol.
A method for treating diabetes, which comprises administering an effective amount of a diacylglycerol to a diabetic patient.
A method for improving lipid metabolism in a diabetic, which comprises administering an effective amount of a diacylglycerol to said diabetic patient.
A method for improving insulin resistance in a diabetic, which comprises administering an effective amount of a diacylglycerol to said diabetic patient.
A method of dietary therapy for a diabetic patient, which comprises administering an effective amount of a diacylglycerol.
A medical food for a diabetic patient, comprising a diacylglycerol.
A processed oil or fat food having insulin resistance improving effect, comprising a diacylglycerol.
Dependencies are inferred from the claim text.