Agents correcting gene expression regulatory error
OwnerTatsuji Enoki, Syusaku Yamashita +3inventors
InventorsTatsuji Enoki, Syusaku Yamashita, Kaori Nishimura, Hiroaki Sagawa, Ikunoshin Kato
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Abstract
The present invention provides a suppressor for unbalance of gene expressions, characterized in that the suppressor comprises, as an effective ingredient, a specified compound; a therapeutic agent or prophylactic agent for a disease that requires modulating unbalance of expressions of a specified gene; and a method for modulating unbalance of gene expressions, characterized by administering to a mammal the above-mentioned compound.
Claims7
A suppressor for unbalance of gene expressions, characterized in that the suppressor comprises, as an effective ingredient, at least one compound selected from a compound represented by the following formula (I):
- 3
- wherein X and Y are H or CH2OH, with proviso that when X is CH2OH, Y is H, and when X is H, Y is CH2OH;
- a compound represented by the following formula (II):
- 4
- wherein R is a residue resulting from removal of one SH group from an SH-group containing compound;
- and a salt thereof.
A method for modulating unbalance of gene expressions, characterized by administering to a mammal at least one compound selected from a compound represented by the following formula (I):
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- wherein X and Y are H or CH2OH, with proviso that when X is CH2OH, Y is H, and when X is H, Y is CH2OH;
- a compound represented by the following formula (II):
- 8
- wherein R is a residue resulting from removal of one SH group from an SH-group containing compound;
- and a salt thereof.
Dependencies are inferred from the claim text.