Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor

A method of inhibiting the development of age-related disorders in a patient in need thereof, comprising administering to said patient pharmaceutically effective amounts of cariporide and ramipril.

A method of inhibiting the development of age-related organ damage in a patient in need thereof, comprising administering to said patient pharmaceutically effective amounts of cariporide and ramipril.

A method of prolonging life in a patient in need thereof, comprising administering to said patient pharmaceutically effective amounts of cariporide and ramipril.

A method of effecting a partial regression of heart failure in patient in need thereof, comprising administering to said patient pharmaceutically effective amounts of cariporide and ramipril.

A method of inhibiting progression of heart failure in a patient in need thereof, comprising administering to said patient pharmaceutically effective amounts of cariporide and ramipril.

The use of pharmaceutically effective amounts of cariporide and ramipril in the preparation of a medicament for inhibiting the development of age-related disorders in a patient in need thereof.

The use of pharmaceutically effective amounts of cariporide and ramipril in the preparation of a medicament for inhibiting the development of age-related organ damage in a patient in need thereof.

The use of pharmaceutically effective amounts of cariporide and ramipril in the preparation of a medicament for prolonging life.

The use of pharmaceutically effective amounts of cariporide and ramipril in the preparation of a medicament for effecting a partial regression of heart failure in a patient in need thereof.

The use of pharmaceutically effective amounts of cariporide and ramipril in the preparation of a medicament for inhibiting progression of heart failure in a patient in need thereof.

A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a pharmaceutically effective amount, or less than pharmaceutically effective amount of cariporide and a pharmaceutically effective amount, or less than a pharmaceutically effective amount of ramipril, provided that the composition is pharmaceutically effective.

A kit for inhibiting the development of age-related disorders, inhibiting the development of age-related organ damage, effecting a partial regression of heart failure, or inhibiting progression of heart failure, in a patient in need thereof, said kit comprising a plurality of separate containers, wherein at least one of said containers contains cariporide and at least another of said containers contains ramipril, and said containers optionally contain a pharmaceutical carrier.