Genetically stable expression vector
AssigneeDuke University
InventorsMatthias Gromeier, Elena Y. Dobrikova
Life of this patent
Estimating the term…
Abstract
The present invention relates, in general, to an expression vector and in particular, to a genetically stable viral expression vector.
Claims22
An expression vector comprising a virus a non-coding regulatory region of which is replaced, in whole or in part, by a heterologous encoding sequence, wherein the function of said replaced regulatory region is dependent upon secondary structure and wherein said heterologous encoding sequence has said function.
An viral vector obtainable by replacing a non-coding structural element of a virus with a heterologous encoding sequence that is a functional mimic of said structural element.
An expression vector comprising RPδ6 and a nucleic acid sequence encoding an antigen operably incorporated therein.
Dependencies are inferred from the claim text.