Polysaccharidic esters of n-derivatives of glutamic acid

Polysaccharidic ester of the compound of formula (I)

• 3
• wherein:
• R2 and R4 independent from one another, are selected in the group consisting of:
• —NH2, —OH, —OCH3, C1-C5 alkyl, ═O and the 6-membered ring containing the two nitrogen atoms is optionally aromatic;
• X and Y are selected in the group consisting of:
• —C(R5)═, —CH(R5)—, —NH—, —N═, wherein R5 represents:
• —H, C1-C5 alkyl, and the ring including X and Y is optionally aromatic;
• Z is selected in the group consisting of:
• —O—, —CH(R10)—, —N(R10)—, wherein R10 represents —H, C1-C5 alkyl, C1-C5 alkenyl, C1-C5 alkynyl, 5-6 membered heterocyclic ring with 1-3 heteroatoms selected in the group consisting of nitrogen, sulphur and oxygen.
• Ar is 1,4phenyl, possibly condensed with one or more 5-6-membered aromatic rings, optionally heterocycles, optionally substituted with R2 as defined above;
• characterized in that only the primary hydroxy groups present on the monosaccharid units of the polysaccharide are either partially or totally esterified with the γ-carboxylic group of the compounds of formula (I).