Combination of cimetidine and cysteine derivatives for treating cancer

A substance consisting of a chemical complex comprising:

• i) a cysteine derivative of Formula I, stereoisomers thereof and/or salts thereof,
• 5
• wherein n is an integer from 1 to 6;
• p is a whole number selected from the group consisting of 0, 1 and 2;
• R1 is a monoradical selected from the group consisting of hydrogen, halogen, sulphate, optionally substituted C1-C8-acylene, optionally substituted C1-C8-alkylene, optionally substituted C3-C7-cycloalkylene, optionally substituted C2-C8-alkenylene and optionally substituted C2-C8-alkynylene;
• R2 is a monoradical selected from the group consisting of hydrogen, halogen, sulphate, optionally substituted C1-C8-alkylene, optionally substituted C3-C7-cycloalkylene, optionally substituted C2-C8-alkenylene and optionally substituted C2-C8-alkynylene;
• and
• R3 is a monoradical selected from the group consisting of hydrogen, sulphate, optionally substituted C1-C8-alkylene, optionally substituted C2-C8-alkenylene, optionally substituted C2-C8-alkynylene, optionally substituted arylene, optionally substituted heteroarylene and
• 6
• wherein p, R1 and R2 are independently selected from their groups as defined above;
• and
• ii) cimetidine or a derivative thereof according to Formula II, and/or salts thereof,
• 7
• wherein s is a whole number from 1-3, t is a whole number from 0-2 and u is a whole number from 1-2;
• R4, R4′, R5, R5′, R6, R6′ are each a monoradical independently selected from the group consisting of hydrogen, halogen, hydroxyl, C1-C6-alkylene, C1-C8-acylene and arylene;
• R7, R8, R9, R10 are each a monoradical independently selected from the group consisting of hydrogen, nitro, C1-6-alkylene, C2-C6-alkenyl, C1-8-acylene and arylene;
• and
• R11 is a monoradical independently selected from the group consisting of hydrogen, halogen, hydroxy, C1-C6-alkylene, C1-C8-acylene and arylene.