Bifunctional glycopeptide antibiotics and combinatorial libararies thereof
OwnerBinyuan Sun, Zhong Chen +1inventors
InventorsBinyuan Sun, Zhong Chen, Daniel Kahne
Life of this patent
Estimating the term…
Abstract
The present invention relates to a the design of a large class of antibiotics comprised of aglycones of vancomycin or derivatives of an aglycone of vancomycin attached to the anomeric site of moenomycin or a moenomycin derivative.
Claims16
An aglycone of vancomycin attached to the anomeric carbon of moenomycin or a moenomycin derivative.
A compound of formula:
- 12
A combinatorial library comprising a plurality of moenomycin saccharide derivatives bonded to at least one aglycone of vancomycin.
A composition comprising a compound comprising an aglycone of vancomycin attached to the anomeric site of moenomycin or a moenomycin derivative.
The composition of claim 16 further comprising a pharmaceutically acceptable salt.
Dependencies are inferred from the claim text.