Novel endoplasmic reticulum-localized protein, remedies containing the same for diseases associated with glycoprotein abnormality, dna encoding this protein and gene remedies containing the same for treating diseases associated with glycoprotein abnormality
OwnerHirohumi Kai, Kazuhisa Yoshitakeinventors
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Abstract
A protein comprising the amino acid sequence set forth in SEQ ID NO: 1 in the Sequence Listing and a mutant thereof, possessing the glycoprotein production regulating activity, DNA comprising the nucleotide sequence set forth in SEQ ID NO: 2 in the Sequence Listing and a mutant thereof, as well as a therapeutic agent using any of the foregoing for the treatment of glycoprotein aberration disorders (e.g., cystic fibrosis), including gene therapy.
Claims7
A protein comprising the amino acid sequence set forth in SEQ ID NO:
- 1 in the Sequence Listing.
A protein comprising an amino acid sequence derivable from the substitution or the deletion of one or more amino acids in the amino acid sequence SEQ ID NO:
- 1 in the Sequence Listing, or from the addition of one or more amino acids to the amino acid sequence set forth in SEQ ID NO:
- 1 in the Sequence Listing, the protein possessing glycoprotein production regulating activity.
DNA comprising the nucleotide sequence set forth in SEQ NO:
- 2 in the Sequence Listing.
DNA comprising a nucleotide sequence derivable from the substitution or the deletion of one or more nucleotides in the nucleotide sequence set forth in SEQ ID NO:
- 2 in the Sequence Listing, or from the addition of one or more nucleotides to the nucleotide sequence set forth in SEQ ID NO:
- 2 in the Sequence Listing.
Dependencies are inferred from the claim text.