Marine actinomycete taxon for drug and fermentation product discovery
AssigneeThe Regents of the University of California
InventorsWilliam Fenical, Paul R. Jensen, Tracy J. Mincer
Life of this patent
Estimating the term…
Abstract
The invention is the discovery of an actinomycete genus, given the name Salinospora gen. nov., that displays an obligate requirement of seawater (Na+) for growth and unique 16S rRNA signature nucleotides. The invention is also the use of the genus for the production and discovery of active biomolecules such as pharmaceutical agents, agrichemicals, immunomodifiers, enzymes and enzyme inhibitors.
Claims12
A genus within the order Actinomycetales comprising an obligate requirement of sodium for growth and the presence of characteristic 16S rRNA sequences.
A method for producing biomolecules comprising
- growth of a strain of actinomycete with an obligate requirement of sodium for growth and characteristic 16S rRNA sequences, and
- collection of the actinomycete or growth media containing the biomolecule.
A method for drug discovery comprising
- growth of a strain of actinomycete with an obligate requirement of seawater for growth and characteristic 16S rRNA sequences,
- collection of the actinomycete or growth media, and
- analysis of actinomycete or growth media for pharmacological activity.
Dependencies are inferred from the claim text.