Mitogenic oxygenases
AssigneeEmory University
InventorsKathy K. Griendling, Bernard P. Lassegue, J. David Lambeth, Rebecca S. Arnold, Guangjie Cheng
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Abstract
The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.
Claims26
A protein capable of stimulating superoxide production, wherein the protein comprises mox or duox, a fragment thereof or a conservative substitution thereof.
Dependencies are inferred from the claim text.