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US 2003/0157669 A1Published application
Ansamitocins
AssigneeSmithKline Beecham Corporation
InventorMark Fulston
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Abstract
Improved purification methods for ansamitocins are disclosed.
Claims16
A method for preparing purified ansamitocins comprising the steps of:
- a. culturing an ansamitocin-producing microorganism in a liquid culture medium;
- b. treating the culture medium to facilitate solvent extraction of ansamitocins;
- c. extracting ansamitocins from the culture medium with an aromatic hydrocarbon solvent;
- d. concentrating the extracted ansamitocins;
- and
- e. purifying the ansamitocins by crystallization.
3 more elements
A method for preparing purified ansamitocins comprising the steps of:
- a. culturing an ansamitocin-producing microorganism in a liquid culture medium;
- b. extracting ansamitocins from the culture medium with an aromatic hydrocarbon solvent;
- c. concentrating the extracted ansamitocins;
- and
- d. purifying the ansamitocins by crystallization.
2 more elements
Dependencies are inferred from the claim text.