Novel human metabotropic glutamate receptor
AssigneeNPS Pharmaceuticals, Inc.
InventorsKaren J. Krapcho, Thomas M. Stormann, Cynthia Levinthal, Lance G. Hammerland, Laura Storjohann
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Abstract
A novel human metabotropic glutamate receptor (mGluR) protein is identified, sequenced, and cloned. The receptor may be used to screen for compounds that modulate the activity of the mGluR. The recombinant mGluR as well as compounds that modulate mGluR activity may be used in the diagnosis and treatment of neurological disorders and diseases.
Claims4
A calcium receptor/metabotropic glutamate receptor chimeric receptor comprising an extracellular domain of a G-protein coupled calcium receptor and a seven transmembrane domain and an intracellular cytoplasmic tail domain contained in the amino acid sequence of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.