Oxidised fragments of apolipoprotein B and their use
OwnerJoe Lunec, Ruth Bevan +1inventors
InventorsJoe Lunec, Ruth Bevan, Helen Griffiths
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Abstract
There is disclosed a molecule having the sequence of SEQ ID NO: 1 or a partially modified form thereof or an analogue thereof, lysine 5 being conjugated with MDA, and which inhibits uptake by the high affinity LDL receptor of LDL or a partially modified form thereof.
Claims22
A molecule having the sequence of SEQ ID NO:
- 1 or a partially modified form thereof or an analogue thereof, lysine 5 being conjugated with MDA, and which inhibits uptake by the high affinity LDL receptor of LDL or a partially modified form thereof.
A molecule having the sequence of SEQ ID NO:
- 2 or a partially modified form thereof or an analogue thereof, lysine 5 being conjugated with MDA, and which inhibits uptake by the high affinity LDL receptor of LDL or a partially modified form thereof.
A molecule having the sequence of SEQ ID NO:
- 3 or a partially modified form thereof or an analogue thereof, lysine 7 being conjugated with MDA, and which inhibits uptake by the high affinity LDL receptor or LDL or a partially modified from thereof.
A molecule according to any one of the preceding claims, being an immunogen.
A molecule according to any one of the preceding claims for use in a method of treatment or diagnosis of the human or animal body.
Dependencies are inferred from the claim text.