Biocatalysts and method therefor

A method for the screening of cells having at least two distinct biotransforming catalysts combined therein, the method selected from the group consisting of:

• a. providing multiple wells, each of the multiple wells containing cells having at least two distinct biotransforming catalysts combined therein;
• and
• b. providing multiple wells, each of the wells containing different cells having at least two distinct biotransforming catalysts combined therein;
• then allowing cells within the well to catalyze a reaction with a compound within each well, and analyzing the results of any reactions within each well to determine any functional activity of cells within each well.

A method for producing a combinatorial array of biocatalysts comprising the steps of:

• a) providing a host cell;
• b) recombining one biotransformation gene for modifying a chemical substrate into the host cell;
• c) thereby producing at least one recombinant strain comprising a biocatalyst;
• d) then inserting the at least one recombinant strain comprising a biocatalyst into at least two sections of an array of biocatalysts.